Savillex Technical Note: CO2 Ingress Testing on Purillex PETG Square Media Bottles

Irgafos 168 (Tris(2,4-di-tertbutylphenyl)phosphite) is a commonly used antioxidant in plastics, particularly in polyethylene terephthalate glycol (PETG) and other polymeric materials. Its primary function is to prevent the oxidative degradation of polymers, extending their shelf life and maintaining their structural integrity. However, the presence of Irgafos 168 in materials used in biopharmaceutical and cell culture applications has raised concerns about its potential impact on cell growth.

Based on industry concerns of the presence of Irgafos 168 and its potential negative impact on cell growth, testing was initiated to characterize and gather baseline information on Savillex Purillex ® PETG Square Media Bottles via a third party testing facility (Aspen Research, Maple Grove, MN, USA).

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